Public health expert Mike Osterholm discusses outbreak investigations, pandemics, and the risky path the US is taking abandoning innovative vaccine technology and issuing poorly-informed recommendations. Mike’s motivation to leave his small town in Iowa to become a disease detective was driven by a steady diet of “The Medical Detectives” by Berton Roueche. As an epidemiologist, he helped solve hamburger-associated thyrotoxicosis, a tampon-related epidemic of toxic-shock in 1980, and a decades-old cluster of mysterious pneumonia cases called “Austin pneumonia”. Recently, he directed his energy toward filling the gap created when CDC’s science-backed Advisory Committee on Immunization Practices was dismantled and replaced with political appointees. Mike’s new book “The Big One: How We Must Prepare for Future Deadly Pandemics” was published in September, 2025.

