Toxic Burgers, Toxic Shock, & Vaccine Talk with Mike Osterholm

Public health expert Mike Osterholm discusses outbreak investigations, pandemics, and the risky path the US is taking abandoning innovative vaccine technology and issuing poorly-informed recommendations. Mike’s motivation to leave his small town in Iowa to become a disease detective was driven by a steady diet of “The Medical Detectives” by Berton Roueche. As an epidemiologist, he helped solve hamburger-associated thyrotoxicosis, a tampon-related epidemic of toxic-shock in 1980, and a decades-old cluster of mysterious pneumonia cases called “Austin pneumonia”. Recently, he directed his energy toward filling the gap created when CDC’s science-backed Advisory Committee on Immunization Practices was dismantled and replaced with political appointees. Mike’s new book “The Big One: How We Must Prepare for Future Deadly Pandemics” was published in September, 2025.

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Public health expert Mike Osterholm discusses outbreak investigations, pandemics, and the risky path the US is taking abandoning innovative vaccine technology and issuing poorly-informed recommendations. Mike’s motivation to leave his small town in Iowa to become a disease detective was driven by a steady diet of “The Medical Detectives” by Berton Roueche. As an epidemiologist, he helped solve hamburger-associated thyrotoxicosis, a tampon-related epidemic of toxic-shock in 1980, and a decades-old cluster of mysterious pneumonia cases called “Austin pneumonia”. Recently, he directed his energy toward filling the gap created when CDC’s science-backed Advisory Committee on Immunization Practices was dismantled and replaced with political appointees. Mike’s new book “The Big One: How We Must Prepare for Future Deadly Pandemics” was published in September, 2025.

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The views expressed by the host and all guests are their own and are not representative of any current or past employers. This podcast and affiliated content are not medical advice.